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Therapeutic dosing protocols may include: Initial high-dose therapy to correct deficiency Maintenance therapy to prevent recurrence Adjusted dosing based on patient response and laboratory results Administration Frequency Guidelines How often to take cyanocobalamin depends on the type and your health

In addition to supplementation, it may also be necessary to make dietary changes to ensure adequate intake of vitamin B12-rich foods

Their bioavailability, or the amount absorbed, varies between oral and IV/IM routes