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Nicotinic acid is a precursor for biosynthesis of nicotinamide adenine dinucleotide (NAD + ), which is an essential co-factor for cellular regulation to support various metabolic functions ( + is synthesized through two pathways: de novo and salvage pathways (Figure 1) ( FIGURE 1 + kinases

5 mg vial + 1 mL bacteriostatic water = 5 mg/mL 2 mg dose = 0.4 mL (40 units on a standard insulin syringe) 2.5 mg dose = 0.5 mL (50 units) 5 mg vial + 2 mL bacteriostatic water = 2.5 mg/mL 2 mg dose = 0.8 mL (80 units) 2.5 mg dose = 1 mL (100 units, full syringe) 10 mg vial + 2 mL bacteriostatic water = 5 mg/mL 2 mg dose = 0.4 mL (40 units) 2.5 mg dose = 0.5 mL (50 units) 5 mg dose = 1.0 mL (100 units) Most people stick with the 1 mL per 5 mg ratio because the numbers come out clean and easy to draw

Fertility and Sterility , 70(6), 1101-1108