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If this is true, then it is likely that either the upregulated process of melanin biosynthesis, the increased amount of melanin in the melanocytes, or both, occurring in the fields of benign oral melanin hyperpigmentation, constitute risk factors for transformation into oral mucosal melanomata

Microscopically, solid granules in a chronic inflammatory cell infiltrate present the same histopathologic aspect in both graphite and amalgam tattoos

Additionally, ultrasound vocalization (USV) testing was used to measure communication deficits

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