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Collectively, synergistic activity of VP in vivo may be attributed to improved systemic exposure to co-treated drugs by modulating mammalian transporters without inhibiting bacterial efflux pumps (152)

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Yang J, Antin P, Berx G, Blanpain C, Brabletz T, Bronner M, et al

Moreover, observed terpene blends depend on the mode of extraction with differences between volatiles that are directly absorbed from the bark surface or extracted from the phloem using organic solvents (Hietz and Baier 2005)