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During periods of stress, your body rapidly depletes its Vitamin C stores to produce cortisol, the primary stress hormone

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The analysis of the optimized structures of the MichaelisMenten complex indicate that the polar residues at position 13 (Cys or Ser) stabilize the deprotonated GS , which in turn acts as the catalytic Brnsted base and abstracts the proton at position C2 of substrate 7 (Extended Data Fig

While chemical resolution remains the primary industrial method for R-ALA production [40], enzymatic approachesparticularly engineered ketoreductasesshow promise for more sustainable manufacturing