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To optimize the electrode composition, weight studies were conducted by varying the quantity of the active component from 2 mg to 10 mg while keeping other parameters constant

However, IFN- alone does not directly trigger ferroptosis (56)

Furthermore, studies indicate that melatonin levels in the AH naturally rise in response to increased IOP, suggesting an intrinsic protective mechanism

For example, in humans, it typically takes years to develop visual field loss, and treatment typically starts long time after the onset of disease, whereas in these mice, neurodegeneration starts at 5 W (EAAC1 KO mice) or 3 W (GLAST KO mice) and the treatment was started at the onset of neurodegeneration