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doi: 10.1016/j.phrs.2021.105580, 107

This intermediate is responsible for cyclization, hydrolysis, and base-exchange reactions 133

They were maintained under a 12 h light-dark cycle (lights on from 8:00 AM to 6:00 PM) at a temperature conducive to mouse survival (2325 C) and 50% humidity, with ad libitum access to water and food