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Regeneration of MethylCo(III)B12 is performed by methionine synthase which transfers the methyl group from 5-methyl-tetrahydrofolate (5MTHF) to Co(I)B12

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Symptoms of a vitamin B12 deficiency can include: Constantly feeling worn out or persistent fatigue Muscle mass pains as well as weakness Joint pain Trouble breathing or lack of breath Feeling lightheaded Poor memory Inability to focus well Mood changes, like boosted depression and also stress and anxiety Having uncommon heart issues, such as palpitations Poor oral wellness, consisting of hemorrhaging gum tissues and mouth sores Digestion troubles like looseness of the bowels, queasiness or cramping A poor appetite A a lot more serious shortage could additionally trigger a type of anemia called pernicious anemia, a significant condition that can create memory loss, confusion as well as long-lasting mental deterioration Who would be more in danger for having a vitamin B12 deficiency