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Advanced Analytical Verification: Every batch is validated through HPLC and Mass Spectrometry (MS) to confirm chemical identity and ensure precise peptide purity

Nevertheless, in the past few years, seven randomized phase III clinical trials, which tested other first-line and second-line treatments, in intermediate-stage or advanced-stage HCC patients have not found any obvious OS benefits (Llovet et al., 2015)

Moreover, medical boards underscore the need for strict protocols, yet enforcement remains inconsistent

Overall, this data suggests that these four efflux pumps of different families are all involved in the rescue of the cells from 5-OP toxicity