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It has been reported that suppression of DHAR expression results in a preferential loss of chlorophyll a and less CO 2 assimilation, resulting in decreased rate of leaf expansion, reduced foliar dry weight and premature leaf aging

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The secretion of TNF- and IL-1 induced by HMGB1 in PR cells was blocked by FPS-ZM1 (an inhibitor of the AGER), thus reversing the degeneration of PR in rd1 mice ( 2.2 Microglia As the specialized resident macrophages in the neural retina, microglia constitute a primary population of glial cells ( Despite the absence of consensus on the mechanisms underlying microglial ferroptosis, several genes implicated in this process have been identified

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