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For example, docosahexaenoic acid (DHA) and eicosapentaenoic acid (EPA) found in high concentration in oily fish and fish oil have shown in both in vitro brain cell culture experiments and in vivo animal studies to mitigate inflammatory pathways, through activation of peroxisome proliferator-activated receptor (PPAR) (Reference Mita, Beaulieu and Field23) and the NF-b transcription factor (Reference Paterniti, Impellizzeri and Di Paola24) , both of which are involved in many biological pathways including inflammation

Understanding the specific symptoms that emerge when you mix GHB and alcohol helps explain why this combination can be fatal even when neither substance alone would have caused the same outcome

Cancer Cell 14 , 447457 (2008)