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doi: 10.1007/s000180050041 32 DelisleG.ChampouxM.HoudeM

Synergistic growth inhibitory activity of combined MEK/mTOR pathway blockade in PTEN-null cancers

Conversely, since GC excess stimulates hypothalamic AMPK (driving increased appetite) and hepatic AMPK activity (contributing to fatty liver), adrenal insufficiency should result in AMPK inhibition at these sites