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Many people dont consume enough Vitamin B12 in their diet, particularly vegetarians and vegans due to B12 being found naturally in animal products such as meat, fish, milk, and eggs

While vitamin B 12 deficiency is not a primary test in newborn screening programs, a study showed that markers C3, C3/C2, and C3/C16 exhibit a negative correlation with maternal levels of vitamin B 12 in the first trimester of pregnancy, and thus may bear diagnostic value (Dayaldasani et al., 2014)

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10,53 Despite significant scientific progress in this field, various aspects of AA pathways in the cardiometabolic system remain to be further investigated