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Mechanism of Action Ipamorelin stimulates growth hormone release by mimicking ghrelin, a peptide that binds to the growth hormone secretagogue receptor (GHSR) on the pituitary gland

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J Neuropathol Exp Neurol 64(12):10671079 Pujol A (2016) Novel therapeutic targets and drug candidates for modifying disease progression in adrenoleukodystrophy

However, much of the evidence supporting these anti-inflammatory effects derives from mechanistic and preclinical studies, and their direct relevance in the setting of hyperuricemia-associated inflammation remains to be established through robust clinical investigation