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Pederson RA, Brown JC

However, the rigid piperidine ring of P4S forms a boat conformation to fit less optimally into the hydrophobic subsite C of the substrate binding site

Regulatory summaries note its status and lack of approved human use

The Role of B12 Tablets and Supplements While injections are often necessary for significant deficiencies or malabsorption issues, B12 tablets and oral supplements still play a vital role