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FIGURE 1 3.2 Effects of Wuling Capsule on liver histopathology, serum ALT and AST in HUA rats Histopathology was performed to investigate the effect of Wuling capsules on liver histopathology of HUA rats

To sum up, H 2 S may show down the development of high pulmonary blood flow-induced PH by inhibiting the proliferation of pulmonary VSMCs, promoting collagen degradation, suppressing the inflammatory response, influencing pulmonary hemodynamics and vascular structure, activating the Fas/caspase3 pathway, inhibiting the Bcl-2 pathway, and interacting with NO

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DBS can alleviate motor symptoms, reduce the required dosage of medication, and is considered less invasive and safer compared to neurodestructive surgery, making it the preferred method for surgical treatment at present (Hacker et al., 2018)