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Long-term antiretroviral drug therapy has been associated with a number of metabolic side effects, including insulin resistance and diabetes

Your G6PD gene variants (full article): More articles that reference berberine: NAFLD: Berberine (500mg, 3x per day) resulted in a more significant decrease in liver fat and a greater reduction in weight, HOMAR-IR, and lipid profiles .[ref] PCOS: Several randomized clinical trials have found that berberine is as effective as metformin for PCOS.[ref][ref] SCD1 and metabolism: Berberine decreases SCD1 levels and decreases fatty liver in animal studies.[ref][ref] Leptin: Improved leptin ratios and decreased BMI after three months of berberine (300mg/3x per day).[ref] Psoriasis: Berberine decreases psoriasis symptoms when used topically.[ref][ref] Detailed article on quercetin here

These findings open new avenues for therapeutic intervention, such as targeting mitochondrial quality control, mtDNA release, or cGAS-STING signaling to mitigate neuroinflammation and slow disease progression

Int J Food Microbiol 2009;130:117121.ArticlePubMed 12