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Furthermore, the failing heart also exhibits a marked decrease in key enzymatic activities, such as mitochondrial creatine kinase (CKmito), which operates at the intersection of energy metabolism and oxidative stress (Keceli et al., 2022)

[Google Scholar] 30.Masters B.A., Quaife C.J., Erickson J.C., Kelly E.J., Froelick G.J., Zambrowicz B.P., Brinster R.L., Palmiter R.D