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Symptoms depend on dose and form and can be subtle, so anyone concerned about exposure should be evaluated by a healthcare provider promptly

Excessive animal fat intake may increase the risk of chronic situations such as hyperlipidemia and hypertension (Basak et al., 2022)

Increased cell shrinkage, loss of cellular adhesions, and apoptotic bodies were observed in treated HeLa cells

Several clinical trials have demonstrated that commonly used SGLT2i, including canagliflozin, dapagliflozin, and empagliflozin, can slow down kidney disease progression and reduce morbidity and mortality in patients with CKD, regardless of the presence of diabetes mellitus [155,156,157,158]