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doi: 10.1016/j.radphyschem.2010.02.006

Cramping can be caused by excess levels of prostaglandins, which are linked to inflammation

The C-terminal domain is in aa acid 93124, which has six structures, one structure and 11 H-sites that bind to the substrate, namely Phe105, Ile108, Met109, Val112, Arg113, Tyr116, Ala165, Ile168, Ile211, Trp212 and Ser213 (Fig