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Finally, through multicenter, large-sample clinical cohort studies combined with statistical methods, derive and validate clinically meaningful cutoff values to enable precise patient stratification and individualized treatment

Safety profile and risk assessment FTPP carries more safety concerns than most peptides in the research space

A significant increase in midazolam exposure (respectively from 3.02-fold to 26.41-fold for AUC and from 1.15-fold to 4.27-fold for C max ) in healthy volunteers concomitantly treated with ritonavir alone or ritonavir-boosted PIs has been reported, caused by strong inhibition of CYP3A4 [92,93,94,95]