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(1) Immune checkpoint inhibitor therapy, by blocking immune checkpoint molecules, reactivating the anti-tumor activity of T cells, and thereby enhancing the immune systems attack on tumor cells [243]

Digestive Issues: Vitamin B12 deficiency can cause gastrointestinal symptoms such as constipation, diarrhea, and weight loss

Associate Professor, Universidade Fernando Pessoa Besides being the most important building blocks of proteins aminoacids can also be used as precursors of nitrogen-containing molecules : hemes, nucleotides, glutathione, physiologically-active amines, etc