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Various hematological parameters, including WBC, hemoglobin, and platelet levels, showed no significant changes (31)

However, pegylated uricases are highly immunogenic resulting in the formation of anti-drug antibodies (ADAs) in ~90% of patients 2,7 , correlating with the loss of therapeutic benefit and increased infusion reactions 2

Although miR-214 alone had little effect on the cell viability of AML12 cells (Fig

PSR-1 CTD modulates PSR-1 condensate properties and PSR-1 function Proteins that form phase separated condensates through multivalent interactions usually fall into two categories: those featuring modular domains and those characterized by intrinsically disordered regions (IDRs) 64