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10.1016/S2213-8587(20)30310-7 37 FeigD

FIGURE 7 Discussion We show here that modulating cell redox status by manipulating GSH metabolism primarily affects the IP 3 /Ca 2+ pathway in C6 astroglioma cell line (see scheme in Figure 8)

In addition, oxidative stress leads to the activation of the NF-B signaling pathway and the synthesis of proinflammatory cytokines, thus ROS production by CYP4A11 metabolism of FFA relates to inflammatory reactions (Gao et al

A study exploring the response of Atgstu19 and Atgstu24 mutants to TuMV infection showed significant differences in specific AtGSTU gene expression, virus concentration, ultrastructural alterations, glutathione content, and glutathione transferase and reductase activities compared with Col-0 (wild-type) and mock-inoculated plants ( Atgstu24 mutants had a resistance-like reaction to TuMV (with a high decrease in virus gene expression and movement) compared to susceptible Col-0 plants, suggesting that GSTU24 may suppress plant resistance