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It may promote tumor development in the tumor microenvironment by triggering ferroptosis, which negatively regulates the proliferation and function of CD8 + T cells (Wu J

PMID: 32436359 Biochem PharmacolIsoalantolactone targets NLRP3 to disrupt NLRP3-NEK7 interaction and suppress inflammasome activation

2021;122:p154843

In contrast, neurons prioritize maintaining ion gradients for electrical signaling, with mitochondria concentrated near synapses to support neurotransmitter release