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A proposed mechanism by which LA normalizes tight junction structure to prevent gliadin from crossing the intestinal epithelium is through regulation of the endogenous zonulin pathway

doi: 10.1002/dad2.12101 260 Vzquez-VlezG

Research has demonstrated that melatonin concentrations in the follicular fluid of PCOS patients are significantly lower than in healthy women, and its levels correlate positively with basal FSH, suggesting a potential involvement of melatonin deficiency in the reproductive pathology of PCOS (147)

Cyclooxygenase-2 inhibitor, celecoxib, inhibits the altered hippocampal neurogenesis with attenuation of spontaneous recurrent seizures following pilocarpine-induced status epilepticus