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Their pathological mechanisms are complex and interrelated, with the core issue lying in the progressive dysfunction of mitochondrial function in neuronal cells-where overloaded oxidative stress, depleted energy metabolism, and uncontrolled apoptosis form a vicious cycle

The microspheres combine all the advantages of affinity protein purification (low costs, simplicity, high specificity, and capacity) and magnetic properties to perform efficient manual or automatic quick high-throughput purification

, has been suggested to exert diverse biological activities involving anti-oxidation, anti-inflammation, and anti-apoptosis ( 2 Research progress of SA in inflammation-related diseases Due to the significant anti-inflammatory, anti-oxidative, and anti-apoptotic effects, SA has been investigated for its potential to treat myocardial ischemia-reperfusion injury, liver injury, respiratory diseases, and other inflammation-related conditions including kidney injury, neuroinflammation, psoriasis, rheumatoid arthritis, and osteoarthritis (Table 1)

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