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Argininosuccinate synthetase (AS) represents a potential translational protein liver injury biomarker that was initially observed by Svetlov et al

There is a need for comprehensive risk assessments and safety regulations to mitigate adverse reactions in humans and animals (58)

Research has found that Glaucocalyxin A can significantly improve liver fibrosis in HF mice by increasing the abundance of Muribaculaceae and Bacteroidaceae, reducing levels of AST, ALT, total bile acid (TBA), and inflammatory markers (IL-1, TNF-), ameliorating hepatic pathological damage and collagen deposition, and lowering apoptosis levels [161]

Melatonin collaborates in the inhibition of human telomerase reverse transcriptase (hTERT), a subunit of telomerase that is mainly responsible for the activation of the enzyme [56]