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2.4.1 Brain-derived neurotrophic factor (BDNF) BDNF is the most abundant in hippocampus and cortical regions of the CNS

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The Negative Impacts of Hormone Deficiency Hormonal deficiency is a common side effect of aging

Patients who experience a persistent sensation of tightness at the oral commissure and who present with distortion or retraction of the oral commissure, difficulty controlling a food bolus with chewing or frequent biting of the cheek during chewing, may be considered optimal candidates for botulinum toxin injection into this muscle