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Cells that survive and grow in vivo but are not capable of growing or dividing by conventional laboratory methods

As previously mentioned mTOR integrates nutrient and hormonal signals to regulate growth and has been described as a major modulator of age-related diseases

Furthermore, we summarize current clinical research on anti-inflammatory therapies and discuss promising therapeutic targets

Human pancreatic stellate cell (hPSC) culture and treatments HPSCs (Fenghui Biotechnology Co., Ltd., Changsha, China) were cultured in RPMI 1640 medium (Gibco) with glucose (5.5 mmol/L glucose) supplemented with 10% FBS (Gibco) in an incubator with 5% CO2 at 37 C