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Biochim Biophys Acta 1330:274283 Ivanova LA, Ronzhina DA, Ivanov LA, Stroukova LV, Peuke AD, Rennenberg H (2011) Over-expression of gsh1 in the cytosol affects the photosynthetic apparatus and improves the performance of transgenic poplars on heavy metal-contaminated soil

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Severe renal impairment may affect the use of this medication, though it is not an absolute contraindication