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However, in UC and CD, increased levels of MMPs can occur even in cases with concomitant higher expression of TIMPs (e.g., in fibrotic disease), suggesting that MMPs increased levels cannot be counteracted by TIMPs activity [120]

For example, However, some vitamin D supplements arent affected by what you eat

Some individuals may struggle to absorb enough B12 from their diet, especially those with conditions like pernicious anemia, certain gastrointestinal disorders, or those taking medications that impact absorption

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