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doi: 10.1021/jf803011r 34 El FaqerO.RaisS.ElkoraichiI.El AmraniA.DakirM.ZaidY.et al

This diminished binding to LDLR places ApoE2 homozygous individuals at a greater risk for type III hyperlipoproteinemia, a genetic disorder characterized by elevated plasma levels of cholesterol and triglycerides (Hatters et al., 2006)