glutathione disulfide nov-002 and Glutaredoxin—Key Players in Cellular Redox Homeostasis and Signaling Cell signaling Glutathione induced cleavage of disulfide

Strbe et al., 2021)

The second step is the activation of the NLRP3 inflammasome by so-called DAMPs (danger-associated molecular patterns) and PAMPs (pathogen-associated molecular patterns), leading to assembly of a large inflammasome complex that provides an activation platform for caspase 1 and subsequent cleavage of pro-IL-1 and pro-IL-18 into their active forms (Tschopp and Schroder, 2010)

If this happens to you, try taking your collagen with a small meal or reducing the dosage

Some scientists wonder whether low glutathione levels are at least partly to blame for the free-radical-induced illnesses so common beyond middle age, such as Alzheimers, cancer, and heart disease