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(2001) preclinical study (PMID 11285201) demonstrating that the C-terminal fragment of hGH (residues 177-191, the basis of AOD-9604) inhibits fat cell formation in 3T3-L1 cells, establishing the rationale for AOD-9604 as a lipolytic agent

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For weight management, some patients may use the medication until achieving their goal weight and then attempt to maintain weight loss through lifestyle modifications alone, while others may require continued treatment to prevent weight regain