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Genotoxicity and Carcinogenicity Potential Studies addressing the genotoxicity and carcinogenicity of kava extracts have been reported in the literature, with most of them being recently compiled and discussed by the IARC [6]

However, despite the widespread use of in vitro and in vivo modelssuch as transgenic animal models and brain organoidsto investigate the effects of natural compounds, these systems often fall short in capturing the full complexity of late-onset Alzheimers disease (LOAD)

ECT augmentation of antipsychotics in severely ill schizophrenia: a naturalistic, observational study

Carretero, M., Ruiz-Torres, M., Rodriguez-Corsino, M., Barthelemy, I