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Transplantation of gut microbiota derived from Alzheimer's disease mouse model impairs memory function and neurogenesis in C57BL/6 mice

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As a result, experiments can be planned around a known molar mass and a known sequence, and results are easier to compare between laboratories

-syn aggregation leads to increased iron deposition and ferroptosis in PD mice, while MT1 knockout reduces the resistance of neurons to ferroptosis by inhibiting the SIRT1/Nrf2/HO-1/GPX4 pathway and inhibiting the expression of ferritin FTH1, resulting in more ferrous ion release, which further leads to more DA neuron loss and severe dyskinesia