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To evaluate patient-reported effects of treatments, we defined a NAS based on patients responses on the impact of each treatment on their overall condition: The number of positive and negative feedback corresponds to patients reporting any level of improvement or worsening, respectively

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HYPOGLYCEMIA is a functional low blood sugar level where levels may be within normal limits via blood work but occurs when one has drops in blood sugar throughout the day (often related to low adrenal function)

Specifically, mutation of the conserved SUMO motif in SHMT1 prevents its translocation to the nucleus [75]