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JAMA Oncol

doi:10.1007/s00775-012-0879-y Boireau A, Marechal PM, Meunier M, Dubedat P, Moussaoui S (2000) The anti-oxidant ebselen antagonizes the release of the apoptogenic factor cytochrome c induced by Fe 2+ /citrate in rat liver mitochondria

Conversely, suppose the glutathione production process (or the trans-sulfuration pathway) is not functioning correctly

Hypokalemia also directly affects the electrophysiological activity of myocardial cells, causing electrocardiographic abnormalities (such as U waves and prolonged QT interval) and significantly increasing the risk of fatal arrhythmias (e.g., torsades de pointes) (Elinav and Chajek-Shaul, 2003