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Interestingly, direct fibroblast proliferation as measured by cell assay was not significantly affected, suggesting the mechanism is more nuanced than simple cell replication

Phase III randomized, placebo-controlled, double-blind study of monosialotetrahexosylganglioside for the prevention of oxaliplatin-induced peripheral neurotoxicity in stage II/III colorectal cancer

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Most patients undergo surgery combined with adjuvant and/or neoadjuvant chemotherapy, depending on the stage of the disease, followed by a long course of SERM if the cancer cells express hormonal receptors