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Anti-integrin therapy Movement of leucocytes into the intestinal mucosa facilitates the inflammatory response in IBD

ICI therapies disrupt the sensing of inhibitory receptor signals delivered from the transformed tissue by tumor-specific T or NK cells to reinvigorate their cytotoxic capacity ( In spite of the apparent effectiveness of ICI-based immunotherapies, they often work only in a subset of patients ( 2 Materials and methods 2.1 Ethics approval and consent to participate Fresh blood samples were obtained from healthy volunteers and patients in accordance to the Helsinki declaration

Indo HP, Yen HC, Nakanishi I, Matsumoto K, Tamura M, Nagano Y, et al