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Unresolved renal inflammation could also trigger cell apoptosis and fibrosis by releasing pro-apoptotic, pro-fibrotic growth factors, cytokines, and chemokines ( Cell apoptosis and glomerular injuries are observed during renal ischemia

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Preclinical investigations utilizing comorbid models of heart failure and cognitive impairment have shown that DMF administration leads to significant improvements in both cardiac function and cognitive performance

Chez le rat, on a pu localiser une activit ALDH dans l'pithlium respiratoire ( l'exclusion de l'pithlium olfactif), alors que cette localisation se situe au niveau du rein chez la souris et au niveau du cortex et des tubules rnaux chez le chien, le rat, le cobaye et le babouin