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Pre-treatment with AGE has been shown to attenuate A-induced learning and memory deficits in mice, as detected by the Y-maze test and a passive avoidance test

If the committee recommends it, and the FDA follows that recommendation (which it typically does), the peptide (or peptides) will be added to the list of active pharmaceutical ingredients that licensed pharmacies can use for compounding drugs

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Neuroplasticity driven by HGF/c-Met signaling includes upregulation of brain-derived neurotrophic factor (BDNF), activation of postsynaptic density protein-95 (PSD-95), and increased expression of GluN2B-containing NMDA receptors