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When electrocardiography was performed, the rats in the study had signs of heart failure and ischemic signs

PubMed Wang, Y., Feng, Z., & Yu, L

Previous studies have shown that these effects were regulated by cholesterol metabolism and macrophage colony-stimulating factors via Apoe 55

In support of its pro-longevity profile, researchers have noted that higher MOTS-c levels correlate with healthier aging markers in both animals and humans, implying that maintaining MOTS-c might benefit aging tissues