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Importantly, as shown in the first row, LASSS supplementation effectively prevented an increase in the nitration level of ECM-HGF, whereas GSSSG did not demonstrate efficacy, inconsistent with its potent potential shown in in vitro experiments described earlier (see Figure 1b)

339,340,341 During reperfusion after myocardial infarction, downregulation of zinc transporter ZIP7 increases mitochondrial zinc ions, leading to mitochondrial depolarization and up-regulation of the PINK1-Parkin pathway, which enhanced mitophagy and reduced infarct size

MSCs, for instance, have the ability to release substances that prevent ferroptosis, shielding lung cells from iron-dependent lipid peroxidation (89)