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Neither the newly-emerging pathogenic variants nor those that disappeared after NAC showed a significant correlation with recurrence (Additional File 14)

The role of oxidative stress in depressive disorders

In rodents, enteral administration of acetate and butyrate has been shown to induce the expression of beta-defensin and histone inhibitor-related antimicrobial peptides in intestinal epithelial cells in a GPR43-mediated manner as a means of protecting the intestinal barrier and organizing the inflammatory response induced by, among others, LPS (173)