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Normalization of the transfection efficiency was performed by a firefly luciferase encoded by the same plasmid (Fig

In skeletal muscle, androgens enhance protein synthesis and intracellular amino acid recycling, promote myofiber hypertrophy, increase glycolytic flux and the number of myonuclei, and induce the proliferation of satellite cells [24,25,26,27]

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indeed, it has been shown that mice genetically lacking miR-378 and miR-378* are resistant to high-fat-diet-induced obesity and display enhanced mitochondrial FA metabolism and elevated oxidative capacity of insulin-target tissue 90