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Glutathione is a powerful antioxidant that helps reduce oxidative stress and may influence the production of melanin, the pigment responsible for skin color

Moreover, a multicentric, double-blind, placebo-controlled, randomized trial that used the same methodology found that in patients who are suffering from stage I or II HNSCC and on radiation therapy while taking 400 IU of -tocopherol daily had a significantly higher incidence of subsequent primary malignancies (60/1000 person-years) compared to those on placebo (25/1000 person-years)

This study was reported in accordance with the ARRIVE guidelines

PMID: 40 LiYHuangZPanSFengYHeHChengSet al