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doi: 10.1002/14651858.CD007677.pub4 66 EsfandyariSElkafasHChughRMParkHNavarroAAl-HendyA

The ECM not only determines tissue structure but also regulates many cellular processes through determining the bio-availability of cytokines, chemokines and growth factors, 85,86,87 and by directly influencing the migration and activation of cells 83,88 hence influencing immune responses