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p53 prevents neurodegeneration by regulating synaptic genes

We found that both doses of CHIE (0.72%, 2.16% in drinking fluid, m/v) increased the enzyme activity level of GST (Figure 5J) and reduced the level of AST (Figure 5I) in serum

It has been observed that repeated doses of DCA resulted in loss of GSTZ1-1 protein and activity, probably due to post-translationally modifications of the enzyme 85